Potential Side Effects with Benzocaine gels

For Healthcare Professionals


Dermatologic side effects have included contact dermatitis and urticaria.


Local side effects have included burning and stinging.


Other side effects have included edema.


Cardiovascular side effects have included angioedema.


Hematologic side effects have included methemoglobinemia. The FDA continues to receive reports of methemoglobinemia from postmarketing reporting.

Benzocaine topical Pregnancy Warnings

Benzocaine topical has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Benzocaine topical is only recommended for use during pregnancy when benefit outweighs risk.

Benzocaine topical Breastfeeding Warnings

There are no data on the excretion of benzocaine topical into human milk.

EjectDelay® is an over-the-counter (OTC) FDA compliant medicine used for the delay of premature ejaculation in men.


Do not use EjectDelay® if you are allergic to benzocaine. Discuss your general health status with your doctor to ensure that you are healthy enough to engage in sexual activity. If you experience discomfort during sex, seek immediate medical help. EjectDelay® should not be used with other PE treatments. EjectDelay® should not be used with any topical product containing lidocaine. EjectDelay® does not protect against sexually transmitted diseases, including HIV. Read the potential side effects before using EjectDelay®.